RECENT PUBLICATIONS

2018

Kate ER Hollinshead, Haydn Munford, Katherine Eales, Chiara Bardella, Chunjie Li, Cristina Escribano-Gonzalez, Alpesh Thakker, Yannic Nonnenmacher, Katarina Kluckova, Mark Jeeves, Robert Murren, Federica Cuozzo, Dan Ye, Giulio Laurenti, Wei Zhu, Karsten Hiller, David J Hodson, Wei Hua, Ian Tomlinson, Christian Ludwig, Ying Mao and Daniel A Tennant. Cell Reports (in revision)

2017

Mei Chong, Anusha Jayaraman, Silvia Marin, Vitaly Selivanov, Pedro R. de Atauri Carulla, Daniel A. Tennant, Marta Cascante, Ulrich L. Günther and Christian Ludwig. Combined NMR and MS analysis for tracer based metabolic flux experiments. Angewandte Chemie, 2017. 15, 4204-4210

 

Gavin McNee, Deborah S Williams, Wenbin Wei, Angelique Barkhuisen, David B Bartlett, Sarah Essex, Seetharam Anandram, Andrew Filer, Paul AH Moss, Guy Pratt, Supratik Basu, Clare C Davies and Daniel A Tennant. Citrullination of histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma. Leukemia, 2017. 31(2), 373-81

Jay Nath, Tom B. Smith, Kamlesh Patel, Sam R. Ebbs, Alex Hollis, Daniel A Tennant, Christian Ludwig and Andrew R Ready. Metabolic differences between cold stored and machine perfused porcine kidneys: A 1 H NMR based study. Cryobiology, 2017. (47), 115-120

2016

Jay Nath, Thomas B Smith, Alexander Hollis, Samuel Ebbs, Sefa Canbilen, Daniel A Tennant, Andrew R Ready and Christian Ludwig. 13C glucose labelling studies using 2D NMR is a useful tool for determining ex vivo whole organ glycolytic metabolism during hypothermic machine perfusion of kidneys. Transplantation Res, 2016. 5 (1):7

G Laurenti and DA Tennant. Isocitrate dehydrogenase (IDH), succinate dehydrogenase (SDH), fumarate hydratase (FH): three players for one phenotype in cancer? Biochemical Society Transactions, 2016. 44 (4), 1111-1116

 

KM Koczula, C Ludwig, R Hayden, L Cronin, Guy Pratt, D Tennant, M Drayson, CM Bunce, FL Khanim and UL Guenther. Metabolic plasticity in CLL: Adaptation to the hypoxic niche. Leukemia, 2016. 30(1):65-73

 

Kate ER Hollinshead and Daniel A Tennant. Mitochondrial metabolic remodelling in response to genetic and environmental perturbations. WIREs Syst Biol Med, 2016. doi: 10.1002/wsbm.1334

 

He, S., Jia, G., Zhu, Z., Tennant, D. A., Huang, Q., Tang, K., Liu, J., Musolesi, M., Heath, J. & Yao, X. Cooperative Co-evolutionary Module Identification with Application to Cancer Disease Module Discovery.  IEEE Transactions on Evolutionary Computation. 2016. 10.1109/TEVC.2016.2530311

 

KL Eales, KER Hollinshead and DA Tennant. Hypoxia and metabolic adaptation of cancer cells. Oncogenesis, 2016. 5(1):e190

2015

Charlotte Lepoutre-Lussey, Kate ER Hollinshead, Christian Ludwig, Mélanie Menara, Aurélie Morin,  Luis-Jaime Castro-Vega, Seth J Parker, Maxime Janin, Cosimo Martinelli, Chris Ottolenghi, Christian Metallo, Anne-Paule Gimenez-Roqueplo, Judith Favier* and Daniel A Tennant*. Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism. Nature Communications. 2015. 6:8784

 

C Ludwig, DS Williams, DB Bartlett, S Essex, G McNee, JW Allwood, E Jewell, A Barkhuisen, H Parry, S Basu, WB Dunn, PAH Moss, G Pratt, DA Tennant. Alterations in bone marrow metabolism are an early and consistent feature during the development of MGUS and multiple myeloma. Blood Cancer Journal, 2015. 5:e359

 

Joerg M. Buescher, Maciek R. Antoniewicz, Laszlo G. Boros…Daniel A. Tennant… Jamey D. Young, Nicola Zamboni and Sarah-Maria Fendt. A roadmap for interpreting 13C metabolite labelling patterns from cells. Current Opinion in Biotechnology, 2015. 34:189-201

 

Alison J Guy, Jay Nath, Mark Cobbold, Christian Ludwig, Daniel A Tennant, Nicholas G Inston, Andrew R Ready. Metabolomic Analysis of Perfusate During Hypothermic Machine Perfusion of Human Cadaveric Kidneys. Transplantation, 2015. 99(4):754-759

2014

Jay Nath, Allison J Guy, Thomas B Smith, Mark Cobbold, Nicholas G Inston, James Hodson, Daniel A Tennant, Christian Ludwig, Andrew R Ready. Metabolomic perfusate analysis during kidney machine perfusion: the pig provides an appropriate model for human studies. PLoS ONE, 2014. doi: 10.1371/journal.pone.0114818

      

Liu Y, Tennant DA, Zhu Z, Heath JK, Yao X, He S. DiME: A scalable disease module identification algorithm with application to glioma progression. PLoS ONE, 2014. 9(2):e86693.

 

Howell, NJ and Tennant DA. The role of hypoxia inducible factors in ischemia-reperfusion injury. Hypoxia, 2014. 2:107-115

 

Wilson GK, Tennant DA and McKeating JA. Hypoxia and liver injury; current understanding and future directions. Journal of Hepatology, 2014. 61(6):1397-1406

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