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Katarina Kluckova, Alpesh Thakker, Lisa Vettore, Rebecca Hindshaw, Cristina Escribano-Gonzalez, Baksho Kaul, Jacqueline LE Tearle, Judith Goncalves, Gareth G Lavery, Judith Favier and Daniel A Tennant. Succinate dehydrogenase-deficiency in a chromaffin cell model retains metabolic fitness through the maintenance of mitochondrial NADH oxidoreductase function. FASEB J. (2020). 34(1), 303-315


L Vettore, RL Westbrook and DA Tennant. New aspects of amino acid metabolism in cancer. Br J Cancer, 2019. 1-7

Jill Mary Brooks, Albert Nobre Menezes, Maha Ibrahim, Lucinda Archer, Neeraj Lal, Christopher J Bagnall, Sandra V von Zeidler, Helen R Valentine, Rachel J Spruce, Nikolaos Batis, Jennifer L Bryant, Margaret Hartley, Baksho Kaul, Gordon B Ryan, Riyue Bao, Arun Khattri, Steven P Lee, Kalu UE Ogbureke, Gary Middleton, Daniel A Tennant, Andrew D Beggs, Jonathan Deeks, Catharine ML West, Jean-Baptiste Cazier, Benjamin E Willcox, Tanguy Y Seiwert, Hisham Mehanna. Development and Validation of a Combined Hypoxia and Immune Pre Prognostic Classifier for Head and Neck Cancer. Clin Can Res, 2019. 25(17), 5315-5328

Yasir S Elhassan, Katarina Kluckova, Rachel S Fletcher, Mark Schmidt, Antje Garten, Craig L Doig, David M Cartwright, Lucy Oakey, Claire V Burley, Ned Jenkinson, Martin Wilson, Samuel J E Lucas, Ildem Akerman, Alex Seabright, Yu-Chiang Lai, Daniel A Tennant, Peter Nightingale, Gareth A Wallis, Konstantinos N Manolopoulos, Charles Brenner, Andrew Philp, Gareth G Lavery. Nicotinamide riboside augments the human skeletal muscle NAD+ metabolome and induces transcriptomic and anti-inflammatory signatures in aged subjects: a placebo-controlled, randomized trial. Cell Reports, 2019. 28(7); 1717-1728

Bennett, C.D., Gill, S.K., Kohe, S.E., Wilson, M.P., Davies, N.P., Arvanitis, T.N., Tennant, D.A. and Peet, A.C. Ex vivo metabolite profiling of paediatric central nervous system tumours reveals prognostic markers. Scientific Rep, (2019). 9(1), 10473

Lucy A. Oakey, Rachel S. Fletcher, Yasir S. Elhassan, David M. Cartwright, Craig L. Doig, Antje Garten, Alpesh Thakker, Oliver D. K. Maddocks, Tong Zhang, Daniel A. Tennant, Christian Ludwig, Gareth G. Lavery. Metabolic tracing reveals novel adaptations to skeletal muscle cell energy production pathways in response to NAD+ depletion. Wellcome Open Research, 2019. 3:147


Kate ER Hollinshead, Haydn Munford, Katherine Eales, Chiara Bardella, Chunjie Li, Cristina Escribano-Gonzalez, Alpesh Thakker, Yannic Nonnenmacher, Katarina Kluckova, Mark Jeeves, Robert Murren, Federica Cuozzo, Dan Ye, Giulio Laurenti, Wei Zhu, Karsten Hiller, David J Hodson, Wei Hua, Ian Tomlinson, Christian Ludwig, Ying Mao and Daniel A Tennant. Cell Reports, 2018. 22, 3107-3114

Katherine L Eales, Edward A Wilkinson, Garth Cruickshank, James HR Tucker and Daniel A Tennant. Verteporfin kills hypoxic glioma cells through iron-binding and increased production of reactive oxygen species. Scientific Reports, 2018. 8, 14358

K Kluckova and DA Tennant. Metabolic implication of hypoxia and pseudohypoxia in pheochromocytoma and paraganglioma. Cell Tissue Res, 2018. 372(2), 367-378

TB Smith, K Patel, H Munford, A Peet, DA Tennant, M Jeeves, C Ludwig. High-speed tracer analysis of metabolism (HS-TrAM). Wellcome Open Research, 2018. 3

Christopher D Bennett, Sarah E Kohe, Simrandip K Gill, Nigel P Davies, Martin Wilson, Lisa CD Storer, Timothy Ritzmann, Simon ML Paine, Ian S Scott, Ina Nicklaus-Wollenteit, Daniel A Tennant, Richard G Grundy, Andrew C Peet. Tissue metabolite profiles for the characterisation of paediatric cerebellar tumours. Scientific Reports, 2018. 8(1);11992


Mei Chong, Anusha Jayaraman, Silvia Marin, Vitaly Selivanov, Pedro R. de Atauri Carulla, Daniel A. Tennant, Marta Cascante, Ulrich L. Günther and Christian Ludwig. Combined NMR and MS analysis for tracer based metabolic flux experiments. Angewandte Chemie, 2017. 15, 4204-4210


Gavin McNee, Deborah S Williams, Wenbin Wei, Angelique Barkhuisen, David B Bartlett, Sarah Essex, Seetharam Anandram, Andrew Filer, Paul AH Moss, Guy Pratt, Supratik Basu, Clare C Davies and Daniel A Tennant. Citrullination of histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma. Leukemia, 2017. 31(2), 373-81

Jay Nath, Tom B. Smith, Kamlesh Patel, Sam R. Ebbs, Alex Hollis, Daniel A Tennant, Christian Ludwig and Andrew R Ready. Metabolic differences between cold stored and machine perfused porcine kidneys: A 1 H NMR based study. Cryobiology, 2017. (47), 115-120


Jay Nath, Thomas B Smith, Alexander Hollis, Samuel Ebbs, Sefa Canbilen, Daniel A Tennant, Andrew R Ready and Christian Ludwig. 13C glucose labelling studies using 2D NMR is a useful tool for determining ex vivo whole organ glycolytic metabolism during hypothermic machine perfusion of kidneys. Transplantation Res, 2016. 5 (1):7

G Laurenti and DA Tennant. Isocitrate dehydrogenase (IDH), succinate dehydrogenase (SDH), fumarate hydratase (FH): three players for one phenotype in cancer? Biochemical Society Transactions, 2016. 44 (4), 1111-1116


KM Koczula, C Ludwig, R Hayden, L Cronin, Guy Pratt, D Tennant, M Drayson, CM Bunce, FL Khanim and UL Guenther. Metabolic plasticity in CLL: Adaptation to the hypoxic niche. Leukemia, 2016. 30(1):65-73


Kate ER Hollinshead and Daniel A Tennant. Mitochondrial metabolic remodelling in response to genetic and environmental perturbations. WIREs Syst Biol Med, 2016. doi: 10.1002/wsbm.1334


He, S., Jia, G., Zhu, Z., Tennant, D. A., Huang, Q., Tang, K., Liu, J., Musolesi, M., Heath, J. & Yao, X. Cooperative Co-evolutionary Module Identification with Application to Cancer Disease Module Discovery.  IEEE Transactions on Evolutionary Computation. 2016. 10.1109/TEVC.2016.2530311


KL Eales, KER Hollinshead and DA Tennant. Hypoxia and metabolic adaptation of cancer cells. Oncogenesis, 2016. 5(1):e190



Charlotte Lepoutre-Lussey, Kate ER Hollinshead, Christian Ludwig, Mélanie Menara, Aurélie Morin,  Luis-Jaime Castro-Vega, Seth J Parker, Maxime Janin, Cosimo Martinelli, Chris Ottolenghi, Christian Metallo, Anne-Paule Gimenez-Roqueplo, Judith Favier* and Daniel A Tennant*. Loss of succinate dehydrogenase activity results in dependency on pyruvate carboxylation for cellular anabolism. Nature Communications. 2015. 6:8784


C Ludwig, DS Williams, DB Bartlett, S Essex, G McNee, JW Allwood, E Jewell, A Barkhuisen, H Parry, S Basu, WB Dunn, PAH Moss, G Pratt, DA Tennant. Alterations in bone marrow metabolism are an early and consistent feature during the development of MGUS and multiple myeloma. Blood Cancer Journal, 2015. 5:e359


Joerg M. Buescher, Maciek R. Antoniewicz, Laszlo G. Boros…Daniel A. Tennant… Jamey D. Young, Nicola Zamboni and Sarah-Maria Fendt. A roadmap for interpreting 13C metabolite labelling patterns from cells. Current Opinion in Biotechnology, 2015. 34:189-201


Alison J Guy, Jay Nath, Mark Cobbold, Christian Ludwig, Daniel A Tennant, Nicholas G Inston, Andrew R Ready. Metabolomic Analysis of Perfusate During Hypothermic Machine Perfusion of Human Cadaveric Kidneys. Transplantation, 2015. 99(4):754-759

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