GROUP MEMBERS

Daniel Tennant
Principal Investigator

After graduating from the University of Cambridge with BA (Hons) and MSci in Natural Sciences, Dan undertook a PhD at the University of Manchester under the supervision of Professors Caroline Dive and David Tomlinson. During this time, he investigated the role of hypoxia on diabetic peripheral neuropathy. He then completed a post-doctoral fellowship at the Cancer Research UK Beatson Institute in Glasgow with Professor Eyal Gottlieb, investigating pharmacological means of reactivating normoxic phenotypes in hypoxic cancer cells.

Alpesh has been a research fellow in Dr. Tennant’s group since March 2016, optimising analytical methods for the analysis of stable isotope incorporation into cellular metabolites. Before this he completed a BSc in Pharmacy from the University of Pune in India, an MSc in Biotechnology from Victoria University in Australia and a PhD at Aston University in the UK, where he developed mass spectrometry-based approaches to study the oxidised lipidome in inflammatory disease models.

Katherine Eales
Research Associate
Robert Murren
PhD student
Cristina Escribano
Research Associate
Haydn Munford
PhD student

Katarina joined the Tennant group in 2015 as a research fellow, with a focus on the role of mitochondrial complex II in cancer development. To do this she uses techniques like respirometry and GC-MS metabolic tracing. Katarina gained her Masters and PhD degree at Charles University in Prague, Czech Republic. Her previous work was also centred around complex II but from a different point of view, as being a target for anti-cancer agents resulting in ROS production and apoptosis induction.

Alpesh Thakker
Post-doctoral Research Fellow
Katarina Kluckova
Post-doctoral Research Fellow

Kat graduated with a BSc (Hons) in Biochemistry from the University of Warwick in 2011, after which she continued for two years as an RA investigating the role of the MK2/3 pathway in cognitive flexibility. Kat then undertook an MRes in Biomedical Research at the University of Birmingham, which led to her join the Tennant group for her PhD investigating the role of the Hippo signalling cascade in adult gliomas, with a particular focus on the control of YAP in hypoxia. Kat's current research is aimed at translating her findings into paediatric gliomas.

Rob is currently doing his PhD within the labs of Professor Andrew Peet, a paediatric neuro-oncologist, and Dr Daniel Tennant. Before this he obtained his BSc (Hons) degree in Biomedical Science from the University of Surrey in 2014. The focus of Rob’s PhD is to investigate how changes in oxygen tension affect the metabolism of lipid droplets, and how this may affect the behaviour of highly malignant glioblastoma tumours.

Cristina studied Biotechnology at Polytechnic University of Valencia, Spain, obtaining a first honours dissertation in bioinformatics. After working within the microbiology team at Eurofins Group, Wolverhampton, she joined the Tennant group in 2016 to investigate changes in the bone marrow stroma with the development of multiple myeloma.

PAST MEMBERS

Federica Cuozzo
ERASMUS student
Debbie Williams
Research Technician
Geokmei Chong
PhD student
Tatiana Volpari
PhD student
Giulio Laurenti
Post-doctoral Research Fellow
Gavin McNee
Post-doctoral Research Fellow
Kate Hollinshead
PhD student
Kate Hollinshead
PhD student
Des Ngoga
PhD student

Haydn graduated in 2013 from Leicester University with a BSc in Biomedical Sciences before completing an MRes Cancer Sciences at the University of Birmingham. Haydn's PhD, which he is doing  in both the Tennant and Peet groups, is focused on investigating glutamine metabolism in medulloblastoma, in order to understand the effect of deregulated gluamine metabolism on medulloblastoma phenotype.