GROUP MEMBERS
Daniel Tennant
Principal Investigator
After graduating from the University of Cambridge with BA (Hons) and MSci in Natural Sciences, Dan undertook a PhD at the University of Manchester under the supervision of Professors Caroline Dive and David Tomlinson. During this time, he investigated the role of hypoxia on diabetic peripheral neuropathy. He then completed a post-doctoral fellowship at the Cancer Research UK Beatson Institute in Glasgow with Professor Eyal Gottlieb, investigating pharmacological means of reactivating normoxic phenotypes in hypoxic cancer cells.
Katherine Eales
Post-doctoral Research Fellow
Kat graduated with a BSc (Hons) in Biochemistry from the University of Warwick in 2011, after which she continued for two years as an RA investigating the role of the MK2/3 pathway in cognitive flexibility. Kat then undertook an MRes in Biomedical Research at the University of Birmingham, which led to her join the Tennant group for her PhD investigating the role of the Hippo signalling cascade in adult gliomas, with a particular focus on the control of YAP in hypoxia. Kat's current research is aimed at translating her findings into paediatric gliomas.
Elias Vera-Siguenza
Post-doctoral Research Fellow
Jennie Roberts
Post-doctoral Research Fellow
Jennie joined the Tennant group in 2019 as a research fellow after completing a PhD in cell metabolism. She focuses on optimising analytical methods for the analysis of stable isotope incorporation into cellular metabolites, using techniques such as GC-MS, NMR and LC-MS/MS. Prior to her PhD Jennie worked at the Institute of Cancer Research characterising the distribution, metabolism and pharmacokinetics of novel chemical entities in in vitro and in vivo models of cancer.
Paul Walker
Post-doctoral Research Fellow
Paul graduated with a Master of Chemistry degree from the University of Oxford before completing a PhD in chemical synthesis at the University of Bristol under the supervision of Prof. Matt Crump and Prof. Chris Willis. His project investigated the biosynthesis of bacterial secondary metabolites and antimicrobial natural products. He joined the Tennant group in 2019 and is working on the metabolism of 5-aminolevulinic acid (5-ALA) in brain tumours.
Cristina Escribano
Research Associate
Cristina studied Biotechnology at Polytechnic University of Valencia, Spain, obtaining a first honours dissertation in bioinformatics. After working within the microbiology team at Eurofins Group, Wolverhampton, she joined the Tennant group in 2016 to investigate changes in the bone marrow stroma with the development of multiple myeloma.
Lisa Vettore
PhD student
Lisa completed her Bachelor’s Degree in Biology, followed by a Master’s Degree in Biomedical Sciences with Honours at the University of Padua, Italy. After an internship in Belgium at the VIaams Instituut voor Biotechnologie (VIB), she started her Ph.D. in the Tennant lab to investigate the role of proline metabolism in hypoxic cancers.
Himani Rana
PhD student
Himani graduated with a MSci in Biochemistry and Molecular Medicine from the University of Nottingham in 2019. She then joined the Tennant group to investigate how oxygen tension affects specific amino acid transporters found in the mitochondria, and how this may impact cancer cell metabolism and the development of gliomas.
Rebecca Westbrook
PhD student
Becky graduated from the University of Reading with a BSc in Biomedical Sciences, before completing an MRes at the University of Birmingham in Integrative Physiology. Her PhD project investigates mitochondrial proline synthesis in response to hypoxia in cancer.